Rudolf Vrabec's CV

PharmDr. Rudolf Vrabec, Ph.D.

Assistant professor & researcher

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About Me

I like nature, plants, phytochemistry, and computer technologies. Currently, I am working at Charles Universtity, where I focus on isolation of secondary metabolites of plants which could be used in the therapy of major civilization diseases like Alzheimer's disease or cancer. In my free time, I love learning to code in various programming languages, mainly with focus on web development. Currently, I have also started to study Applied informatics at University of Hradec Králové. When I am resting, I like to hangout with my friends, watch movies, play videogames, or read fantasy books.

Age

ruda.vrabec@seznam.cz

Phone

+420-608429123

↑Professional Skills

Chromatographic methods (TLC, HPLC, GC, CC)

Computer-related work and orientation in scientific databases

Molecular docking and molecular dynamic simulations

Programming in Python, Java

Web development (HTML, CSS, JavaScript, PHP, SQL)

Phytochemistry & Pharmacognosy

Biological tests (antiox., immunomod., inhibit. of AChE/BuChE)

Work with plant tissue cultures

English language (C1)

German language (A2)

↓Work Experience

↓ Education

↓ Publication activity

The anticancer properties of harmine and its derivatives Timbilla, A. A., Vrabec, R., Havelek, R., Řezáčová, M., Chlebek, J., Blunden, G., Cahlíková, L.

2024

Phytochemistry Reviews; DOI:10.1007/s11101-024-09978-0

Undescribed Amaryllidaceae Alkaloids from Zephyranthes citrina and Their Cytotoxicity Křoustková, J., Kohelová, E., Muthná, D., Kuneš, J., Havelek, R., Vrabec, R., Malaník, M., Suchánková, D., Chlebek, J., Jenčo, J., Kosturko, Š., Cahlíková, L.

2024

Journal of Natural Products; DOI:10.1021/acs.jnatprod.4c00825

Specialized metabolites of the genus Zephyranthes Herb.: a critical review on taxonomy and phytochemistry Šafratová, M., Vrabec, R., Blunden, G., Cahlíková, L., Křoustková, J.

2024

Phytochemistry Reviews; DOI:10.1007/s11101-024-09931-1

Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei infection In Vitro Hradiská Breiterová, K., Ritomská, A., Fontinha, D., Křoustková, J., Suchánková, D., Hošťálková, A., Šafratová, M., Kohelová, E., Peřinová, R., Vrabec, R., Francisco, D., Prudencio, M., Cahlíková, L.

2023

Pharmaceutics, 15, 1007; DOI:10.3390/pharmaceutics15031007

Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer’s Disease Vrabec, R., Blunden, G., Cahlíková, L.

2023

International Journal of Molecular Sciences, 24(5), 4399; DOI:10.3390/ijms24054399

Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): identification of new structural scaffold for treatment of Alzheimer's disease Vrabec, R., Maříková, J., Ločárek, M., Korábečný, J., Hulcová, D., Hošťálková, A., Kuneš, J., Chlebek, J., Kučera, T., Hrabinová, M., Jun, D., Soukup, O., Andrisano, V., Jenčo, J., Šafratová, M., Nováková, L., Opletal, L., Cahlíková, L.

2022

Phytochemistry, 194, 113017; DOI:10.1016/j.phytochem.2021.113017

Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity. Šafratová, M., Křoustková, J., Maafi, N., Suchánková, D., Vrabec, R., Chlebek, J., Kuneš, J., Opletal, L., Bucar, F., Cahlíková, L.

2022

Plants, 11(22), 3034; DOI:10.3390/plants11223034

Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents. Wijaya, V., Janďourek, O., Křoustková, J., Hradiská-Breiterová, K., Korábečný, J., Sobolová, K., Kohelová, E., Hošťálková, A., Konečná, K., Šafratová, M., Vrabec, R., Kuneš, J., Opletal, L., Chlebek, J., Cahlíková, L.

2022

Biomolecules, 12(6), 844; DOI:10.3390/biom12060844

Ex-vivo Immune-stimulating Activity of Scutellaria baicalensis and its Major Flavonoids on Human Immune Cells Vrabec, R., Vokurková, D., Tůmová, L., Cheel, J.

2022

Records of Natural Products, 16(2), 188–193; DOI:10.25135/rnp.264.21.02.1976

Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer’s Disease. Cahlíková, L., Vrabec, R., Pidaný, F., Peřinová, R., Maafi, N., Al Mamun, A., Ritomská, A., Wijaya, V., Blunden, G.

2021

Molecules, 26(17), 5240; DOI:10.3390/molecules26175240

PharmDr. Rudolf Vrabec, Ph.D.

PharmDr. Rudolf Vrabec, Ph.D.

About Me

↑Professional Skills

↓Work Experience

↓ Education

↓ Publication activity

↓ Contact

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